Letrozole Citrate 2.5mg 30 Tablets Letromina is a 3rd generation aromatase inhibitor (AI) used to reduce conversion of Testosterone to Estrogen. Letromina is useful in keeping estrogen in the low-normal range for men on androgen therapy. Many male steroids aromatize to estrogen increasing edema, water weight, fat storage, risk of male breast tissue, and emotional liability. For Male Estrogen issues: 0.6-2.5mg 2-3 times per week and titrate Estradiol (E2) to lower normal range.